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Single-cell WGCNA combined with transcriptome sequencing to study the molecular mechanisms of TRPM4-related genes in obesity with experimental validation

2026-02-15

Abstract excerpt

<title>Abstract</title> <p>While TRPM4 is crucial in immune and metabolic diseases, its role in obesity remains unclear. This study aimed to identify TRPM4-associated key genes in obesity. Obesity-related transcriptomic data were analyzed using single-cell RNA sequencing (scRNA-seq) to identify critical cell types, high-Dimensional Weighted Gene Co-expression Network Analysis (hdWGCNA) to determine module genes,...

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Literature Corpus work
f3048e3f-42e7-58f6-8d3e-0fbb0945f089
DOI
10.21203/rs.3.rs-8754472/v1
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Single-cell WGCNA combined with transcriptome sequencing to study the molecular mechanisms of TRPM4-related genes in obesity with experimental validationDOI 10.21203/rs.3.rs-8754472/v1
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