Article
Single cell RNA sequencing of nc886, a non-coding RNA transcribed by RNA polymerase III, with a primer spike-in strategy
2024-03-23
Abstract excerpt
Single cell RNA sequencing (scRNA-seq) has emerged as a versatile tool in biology, enabling comprehensive genomic-level characterization of individual cells. Currently, most scRNA-seq methods generate barcoded cDNAs by capturing polyA tails of mRNAs, which excludes many non-coding RNAs (ncRNAs), especially those transcribed by RNA polymerase III (Pol III). Although previously thought to be expressed constitutively...
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Identifiers and source
- Literature Corpus work
- f265c38d-3aa3-544c-aca0-8734dda02392
- DOI
- 10.1101/2024.03.20.585884
