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Effective Stimulation Sites and Networks for Substantia Nigra Pars Reticulata Deep Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia

2025-04-13

Abstract excerpt

Deep brain stimulation (DBS) of the substantia nigra pars reticulata (SNpr) is under investigation for managing auditory-verbal hallucinations (AVH) in treatment-resistant schizophrenia (TR-SZ). We assessed acute AVH suppression during initial SNpr-DBS programming in three TR-SZ patients and mapped associated brain network engagement using normative connectomes. One-month post-implantation, monopolar stimulation a...

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Literature Corpus work
f17e012d-6244-5476-b3ce-3853e4f445e5
DOI
10.1101/2025.04.09.25325419
Open publication

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Effective Stimulation Sites and Networks for Substantia Nigra Pars Reticulata Deep Brain Stimulation for Auditory Verbal Hallucinations in SchizophreniaDOI 10.1101/2025.04.09.25325419
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