Article

First-in-human low-intensity focused ultrasound targeting striatal circuits in schizophrenia: feasibility, safety, and effects on hallucinations and striatal-temporal functional connectivity

2026-01-13

Abstract excerpt

<h4>Background</h4> Auditory hallucinations are among the most disabling symptoms in individuals with schizophrenia (SZ) and are linked to aberrant signaling within deep-striatal circuits, such as the nucleus accumbens (NAc) and caudate head (CH). However, causal tests of striatal involvement have been limited by the inaccessibility of these structures using noninvasive neuromodulatory techniques. Low-intensity f...

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Literature Corpus work: 45ec1b38-4cad-5943-8881-1e1097697ab7
DOI: 10.64898/2026.01.10.26343837

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