Article

Skeletal muscle fatigue : investigating the role of cytokines, ROS and mitochondrial function

2016-01-01

Abstract excerpt

Skeletal muscle dysfunction and increased rate of fatigue is observed in a number of disorders. An increase in systemic and/or local pro-inflammatory cytokines has been proposed to modulate the ability of skeletal muscle to generate force, alter mitochondrial bioenergetics and induce reactive oxygen species (ROS) generation in muscle. Evidence suggests cytokines such as Tumour necrosis factor-a (TNF-a) play a majo...

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Literature Corpus work: f15558b0-47f9-5de4-a468-029f231e5c88
DOI: 10.17638/03001668

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