Article

DomainScope: A disease network based on protein domain connections

2019-12-04

Abstract excerpt

Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes. Here, using information about variants sites associated with diseases, a disease network was built, based on their shar...

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Literature Corpus work: f0a99e83-57c2-54ba-ac04-ca0def559c16
DOI: 10.1101/862870

Open publication

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