Article

Directional divergence of Ep300 duplicates in teleosts and its implications

2020-10-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> EP300 is a conserved protein in vertebrates, which serves as a key mediator of cellular homeostasis. Mutations and dysregulation of EP300 give rise to severe human developmental disorders and malignancy. <italic>Danio rerio</italic> is a promising model organism to study EP300 related diseases and drugs; however, the effect of EP300 duplicates derived from teleo...

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Literature Corpus work: f093b131-df53-5c47-9156-4d9b9477f88b
DOI: 10.21203/rs.3.rs-42120/v3

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