Back to search

Article

Prognostic Impact of ER-Staining Patterns and Heterogeneity of ER positive HER2 negative Breast Cancer

2025-04-10

Abstract excerpt

<title>Abstract</title> <p>Background Estrogen receptor (ER) expression is critical in breast cancer treatment. While low ER (1%-9%) resembles triple-negative cancer with chemotherapy efficacy, the significance of “intermediate expression” (≥ 10%) and the therapeutic efficacy remain unclear. This study explores differences in staining patterns and molecular characteristics of ER-low to intermediate expression to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
efc77266-f441-54cc-b361-eecde4fb1e47
DOI
10.21203/rs.3.rs-5574795/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Prognostic Impact of ER-Staining Patterns and Heterogeneity of ER positive HER2 negative Breast CancerDOI 10.21203/rs.3.rs-5574795/v1
Immune and gene-expression profiling in estrogen receptor low and negative early breast cancerSemantic proximity
Clinical outcome and global gene expression data support the existence of the estrogen receptor-negative/progesterone receptor-positive invasive breast cancer phenotype.Semantic proximity
Histopathological and Clinical Features of HER2-Positive Breast Cancers across Hormone Receptor Subgroups: A Cross-Sectional AnalysisSemantic proximity
Combined Hormone Receptor and Human Epidermal Growth Factor Receptor-2 Expression Reflects Inter-and Intra-tumor Heterogeneity in Hormone Receptor-positive/human Epidermal Growth Factor Receptor-2-positive Breast CancerSemantic proximity
The Prognosis and Predictive Value of Estrogen Negative/Progesterone Positive (ER-/PR+) Phenotype: Experience of 1159 Primary Breast Cancer from a Single Institute.Semantic proximity
Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor ExpressionSemantic proximity
Comparison of the response to neoadjuvant therapy between immunohistochemistry HER2 (3+) and HER2 (2+)/ISH-positive early- stage breast cancer: A retrospective multicenter cohort studySemantic proximity
An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancerSemantic proximity
Molecular essence and endocrine responsiveness of estrogen receptor-negative, progesterone receptor-positive, and HER2-negative breast cancer.Semantic proximity
A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscapeSemantic proximity
Estrogen receptor expression in human tumors: A tissue microarray study evaluating more than 18,000 tumors from 149 different entitiesSemantic proximity
Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast CancerSemantic proximity
Select a neighboring publication to make it the new centre.