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Systematic Discordance Between HbA1c and Continuous Glucose Monitoring-Derived Glycaemic Metrics in Paediatric Diabetes: Implications for Treatment Decisions

2025-12-31

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<title>Abstract</title> <p>Background: HbA1c guides paediatric diabetes treatment, but biological factors like erythrocyte lifespan cause differences between HbA1c and CGM measures, risking overtreatment, undertreatment, and misclassification. This study quantifies HbA1c–GMI discordance in children, exploring clinical and biological predictors, including residual beta cell function via C-peptide. <h4>Methods:</h...

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Literature Corpus work
efaf0788-d707-5e2f-8312-7b9fa358db53
DOI
10.21203/rs.3.rs-8356318/v1
Open publication

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