Article

Sum of High-Risk Gene Mutation (SHGM): A Novel Attempt to Assist Differential Diagnosis for Adrenocortical Carcinoma with Benign Adenoma, Based Detection of Mutations of Nine Target Genes.

2020-08-11

Abstract excerpt

<h4>Background: </h4> There has been no research on applying gene detection to differential diagnosis of adrenocortical carcinoma (ACC). We attempted to explore a novel auxiliary method for differential diagnosis between ACC with benign adrenocortical adenoma (ACA), based on mutations of target genes in tissues. Methods Nine genes were chosen as target genes, including TP53, CTNNB1, ARMC5, PRKAR1A, ZNRF3, RB1, AP...

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Literature Corpus work: ef3f8d66-b60c-5a0d-a2ab-1df6dec712aa
DOI: 10.21203/rs.3.rs-54829/v1

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