Article

A Large-Scale Brain Network Mechanism for Increased Seizure Propensity in Alzheimer’s Disease

2021-01-20

Abstract excerpt

People with Alzheimer’s disease (AD) are 6-10 times more likely to develop seizures than the healthy aging population. Leading hypotheses largely consider increased excitability of local cortical tissue as primarily responsible for increased seizure prevalence in AD. However, both local dynamics and large-scale brain network structure are believed to be crucial for determining seizure likelihood and phenotype. In...

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Literature Corpus work: ef1935f1-1d5f-575f-813f-43298e9c78db
DOI: 10.1101/2021.01.19.427236

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