Article

Evaluation of Molecular Targets and Mismatch Repair Deficiency in Gallbladder Cancer

2021-05-28

Abstract excerpt

<title>Abstract</title> <p>PurposeGallbladder cancer (GBC) is most aggressive malignancy having very short survival having heterogeneous incidence, clinical and molecular profile. We evaluated molecular targets and mismatch-repair (MMR) protein expression in North-Indian patients. Method111 cases were subjected to high-resolution melt curve, followed by Sanger sequencing for KRAS, BRAF and PIK3CA. Immunohistochem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eef9b436-d78f-5718-b16f-b2e87ac1f70b
DOI: 10.21203/rs.3.rs-528091/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evaluation of Molecular Targets and Mismatch Repair Deficiency in Gallbladder CancerDOI 10.21203/rs.3.rs-528091/v1Read

Mutation profiling in gallbladder cancer in Indian population.Semantic proximity Read

Genomic and molecular landscape of gallbladder cancer elucidating pathogenic mechanisms novel therapeutic targets and clinical implications.Semantic proximity Read

Gallbladder cancer: a morphological and molecular update.Semantic proximity Read

Low frequency of mismatch repair deficiency in gallbladder cancerSemantic proximity Read

Genomic profiling of gallbladder carcinoma: Targetable mutations and pathways involved.Semantic proximity Read

Genomic landscape of gallbladder cancer: insights from whole exome sequencing.Semantic proximity Read

Identification and prevalence of potentially therapeutic targetable variants of major cancer driver genes in ampullary cancer patients in India through deep sequencing.Semantic proximity Read

Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational ApproachSemantic proximity Read

Gallbladder cancer in Chile: what have we learned?Semantic proximity Read

Association of TERT-CLPTM1L and 8q24 Common Genetic Variants with Gallbladder Cancer Susceptibility and Prognosis in North Indian Population.Semantic proximity Read

Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update.Semantic proximity Read

An Insight Into the Driver Mutations and Molecular Mechanisms Underlying Mucinous Adenocarcinoma of the Rectum.Semantic proximity Read