Article

The Human Leukocyte Antigen Class II Immunopeptidome of SARS-CoV-2 Spike Glycoprotein

2020-09-11

Abstract excerpt

The precise elucidation of the antigen sequences for T-cell immunosurveillance greatly enhances our ability to both understand and modulate humoral responses to viral infection or active immunization. Mass spectrometry was used to identify 529 unique sequences from SARS-CoV-2 spike glycoprotein extracellular domain in a complex with human leukocyte antigen class II molecules on antigen presenting cells from a pane...

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Literature Corpus work: eeecb55d-76cf-5ef7-a2e3-be5bd5416ab4
DOI: 10.2139/ssrn.3671736

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