Article

Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution

2023-04-14

Abstract excerpt

Extracellular vesicles (EVs) secreted by tumors are abundant in plasma, but their potential for interrogating the molecular features of tumors through multi-omic profiling remains widely unexplored. Genomic and transcriptomic profiling of circulating EV-DNA and EV-RNA isolated from a range of in-vitro and in-vivo models of metastatic prostate cancer (mPC) revealed a high contribution of tumor material to EV-load...

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Literature Corpus work: ee7820ea-6508-5f01-86f2-0e7be8d7f3cd
DOI: 10.1101/2023.04.14.536404

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