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Evaluation of Multiplexed Liquid Glycan Array (LiGA) for Serological Detection of Glycan-binding Antibodies

2025-06-27

Abstract excerpt

We test the performance of the multiplexed liquid glycan array (LiGA) technology in serological assays. Specifically, we use LiGA to detect ABO blood group antibodies in human serum. This LiGA, which we name ABO-LiGA, contains ABO blood group trisaccharide glycans with an ethylazido aglycone conjugated to groups of ten multi-barcoded M13 particles carrying dibenzocyclooctyne (DBCO) on p8 proteins. ELISA clonal bin...

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Identifiers and source

Literature Corpus work
edd55ad7-7551-5738-8572-e9cef896b072
DOI
10.1101/2025.06.23.660925
Open publication

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Evaluation of Multiplexed Liquid Glycan Array (LiGA) for Serological Detection of Glycan-binding AntibodiesDOI 10.1101/2025.06.23.660925
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