Article

Cell-autonomous metabolic reprogramming and oxidative stress underlie endothelial dysfunction in acute myocardial infarction

2023-03-01

Abstract excerpt

Compelling evidence has accumulated for the role of oxidative stress on the endothelial cell (EC) dysfunction underlying acute coronary syndromes. However, understanding the metabolic determinants of EC dysfunction has been hampered by the scarcity of appropriate cell models. Here, we have generated and phenotypically characterized EC derived from thrombectomy specimens in patients with acute myocardial infarction...

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Literature Corpus work: ed908cc2-2fe8-5b6d-aa8e-60f9d8affafc
DOI: 10.1101/2023.02.28.530418

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