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Transcriptome analysis of diverse <i>Plasmodium falciparum</i> clinical isolates identifies genes correlating with highly variable expression of merozoite surface protein MSPDBL2

2022-02-18

Abstract excerpt

The merozoite surface protein MSPDBL2 of Plasmodium falciparum is under strong balancing selection and is a target of naturally acquired antibodies. Remarkably, MSPDBL2 is expressed in only a minority of mature schizonts of any cultured parasite line, and mspdbl2 gene transcription increases in response to overexpression of the gametocyte development inducer GDV1, so it is important to understand its natural exp...

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Literature Corpus work
ed5fab9f-fc1b-5aa7-8387-d0513113e9be
DOI
10.1101/2022.02.18.481051
Open publication

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Transcriptome analysis of diverse <i>Plasmodium falciparum</i> clinical isolates identifies genes correlating with highly variable expression of merozoite surface protein MSPDBL2DOI 10.1101/2022.02.18.481051
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