Screening for potential biological markers of chronic kidney disease based on WGCNA and machine learning

Abstract excerpt

<h4>Background: </h4> Chronic kidney disease (CKD) is defined as persistent urinary tract abnormalities, structural abnormalities, or impaired excretory function of the kidneys, which is the 16th leading cause of years of life lost worldwide and places an enormous burden on medical care. However, the mechanisms for the progression of CKD are still poorly understood. Therefore, the aim of this study is to identify...

Topics

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• Genome-Wide Association Study
• Glomerular Filtration Rate
• Kidney Failure, Chronic
• Polymorphism, Single Nucleotide
• Renal Insufficiency, Chronic
• Sequence Analysis, RNA
• Single-Cell Analysis
• Transcriptome

Identifiers and source

Literature Corpus work

ed4fa990-8bd6-5501-a556-077608f80181

DOI

10.21203/rs.3.rs-2532057/v1