Article

A-LAVA: Detecting impact of germline variants on metabolic pathways in cancer genomes

2025-09-04

Abstract excerpt

<h4>ABSTRACT</h4> The metabolic landscape of cancer has been widely studied, especially in the context of somatic mutations. However, the impact of inherited germline variants upon the metabolic genes interaction still remains unexplored. In this work, we present a computational pipeline named A-LAVA for the detection and analysis of germline variants that affect metabolic pathways in cancer. Our pipeline enables...

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Literature Corpus work: ec85eb87-9bfe-5394-a6dc-b647b353e3f5
DOI: 10.1101/2025.08.30.673276

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