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C-terminal region of Rv1039c (PPE15) protein of Mycobacterium tuberculosis targets host mitochondria to induce macrophage apoptosis

2024-02-02

Abstract excerpt

The genome of Mycobacterium tuberculosis (Mtb) encodes a unique family called Proline-Glutamate/Proline-Proline-Glutamate (PE/PPE) gene family, which is exclusive to pathogenic mycobacterium. Several proteins of this family are known to be virulent and utilize host signalling and cell death pathways leading to host immune response modulation, but functions of many of the PE/PPE proteins are yet to be identified. W...

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Literature Corpus work
eb9bad02-f465-58c7-9610-b69a9ae4d00f
DOI
10.21203/rs.3.rs-3910030/v1
Open publication

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C-terminal region of Rv1039c (PPE15) protein of Mycobacterium tuberculosis targets host mitochondria to induce macrophage apoptosisDOI 10.21203/rs.3.rs-3910030/v1
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