Article

High genetic diversity of mpox virus (MPXV) in three different rodent species in the Democratic Republic of the Congo (DRC)

2025-08-28

Abstract excerpt

Altough zoonotic spillover events continue to drive human mpox outbreaks in the Democratic Republic of the Congo (DRC), the wildlife reservoir of mpox virus (MPXV) remains unkown. To address this gap, we screened samples from 2,701 wild mammals, mainly rodents (59.7%), bats (26.4%) and shrews (12.1%). Only six (0.2%) animals were Orthopoxvirus (OPV) PCR positive. Near full-length MPXV sequences were obtained from...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eb56e85e-5523-582b-bec9-f519fe59c68b
DOI: 10.1101/2025.08.28.672325

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

High genetic diversity of mpox virus (MPXV) in three different rodent species in the Democratic Republic of the Congo (DRC)DOI 10.1101/2025.08.28.672325Read

Exploring the genomic basis of Mpox virus-host transmission and pathogenesisSemantic proximity Read

Clade I Mpox virus genomic diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic TransmissionSemantic proximity Read

Animal host range of mpox virusSemantic proximity Read

Mpox Virus: Its Molecular Evolution and Potential Impact on Viral EpidemiologySemantic proximity Read

Genomic sequence analysis of the first mpox virus detected in KenyaSemantic proximity Read

Circulation, viral diversity and genomic rearrangement in mpox virus in the Netherlands during the 2022 outbreak and beyondSemantic proximity Read

Epidemiology and Phylogenomic Characterization of Distinct 2023 and 2024 Mpox outbreaks in Kinshasa, Democratic Republic of the Congo - Evidence for increasingly sustained human-to-human transmission of subclade IaSemantic proximity Read

Overview of Diagnostic Methods, Disease Prevalence and Transmission of Mpox (Formerly Monkeypox) in Humans and Animal ReservoirsSemantic proximity Read

Emergence of Clade Ib Monkeypox Virus—Current State of EvidenceSemantic proximity Read

Molecular epidemiology of recurrent zoonotic transmission of mpox virus in West AfricaSemantic proximity Read

Putative APOBEC3 deaminase editing in MPXV as evidence for sustained human transmission since at least 2016Semantic proximity Read

First cases of mpox Clade I outside of Africa: genetic insights on its evolutionSemantic proximity Read