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Emergence of Clade Ib Monkeypox Virus—Current State of Evidence

24 Jul 2025

Abstract excerpt

Mpox was first identified against the backdrop of the smallpox eradication campaign. Monkeypox virus (MPXV), the causative agent of mpox, has been maintained in animal reservoirs in the forested regions of West and Central Africa as 2 distinct clades; clade I has historically caused more severe infection in Central Africa than clade II, historically found in West Africa. However, rapid reemergence and spread of...

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PMID: 40705002
DOI: 10.3201/eid3108.241551

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