Article

Calendar Period Estimation of Probabilities of Transition in Drug Development

2025-05-15

Abstract excerpt

<h4>ABSTRACT</h4> This paper examines the intricate and high-risk process of drug development. A compound’s journey from target validation to market launch can span 10 to 15 years, with an average cost of one to two billion USD per successful drug. Despite extensive pre-clinical work, only about 10% of drug candidates entering human clinical trials achieve US Federal Drug Administration approval. The primary cause...

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Literature Corpus work: eb012242-1180-511a-aa4f-ee311131a3ac
DOI: 10.1101/2025.05.15.25327693

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