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Functional Deorphanization and Subtype-Selective Pharmacology of Three Tyramine Receptors in the Disease Vector, <i>Aedes aegypti</i>

2026-07-27

Abstract excerpt

Biogenic amines such as tyramine (TA) and octopamine (OA) are central regulators of insect physiology and behaviour, acting through G protein–coupled receptors (GPCRs) to control reproduction, locomotion, metabolism, olfaction and hydromineral homeostasis. Although TA was once considered solely a biosynthetic precursor to OA, it is now recognized as an independent signaling molecule acting through distinct tyramin...

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Literature Corpus work
ea36923b-99f3-5af7-b9da-d945d6ffb412
DOI
10.64898/2026.07.24.740580
Open publication

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