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Let-7b-5p loaded Mesenchymal Stromal Cell Extracellular Vesicles reduce <i>Pseudomonas</i> - biofilm formation and inflammation in CF Bronchial Epithelial Cells

2025-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Cystic Fibrosis (CF) is a multiorgan disease caused by mutations in the CFTR gene, leading to chronic pulmonary infections and hyperinflammation. Among pathogens colonizing the CF lung, Pseudomonas aeruginosa is predominant, infecting over 50% of adults with CF, and becoming antibiotic-resistant over time. Current therapies for CF, while providing tremendous benefits, fail to eliminate persist...

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Literature Corpus work
ea23673a-ad5c-523d-a4a0-279538286600
DOI
10.1101/2025.05.28.656674
Open publication

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Let-7b-5p loaded Mesenchymal Stromal Cell Extracellular Vesicles reduce <i>Pseudomonas</i> - biofilm formation and inflammation in CF Bronchial Epithelial CellsDOI 10.1101/2025.05.28.656674
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