Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of P. aeruginosa

6 Jul 2021

Abstract excerpt

Significance Pseudomonas aeruginosa is one of the leading causes of hospital-acquired infections worldwide primarily due to its ability to develop antibiotic-resistant biofilms. This report describes a mechanism whereby human airway epithelial cells (AECs) increase the ability of antibiotics to kill P. aeruginosa and reduce the formation of drug-resistant biofilms. We demonstrate that human AECs secrete...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Peptides and Activities
Share to Bacterial biofilms and quorum sensing
Share to Inhalation and Respiratory Drug Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34260396
DOI: 10.1073/pnas.2105370118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of P. aeruginosaPMID 34260396Read ↗

Let-7b-5p loaded Mesenchymal Stromal Cell Extracellular Vesicles reduce <i>Pseudomonas</i> - biofilm formation and inflammation in CF Bronchial Epithelial CellsSemantic proximity Read ↗

An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of <i>P. aeruginosa</i>Semantic proximity Read ↗

Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cellsSemantic proximity Read ↗

Evaluating Bacterial Pathogenesis Using a Model of Human Airway Organoids Infected with Pseudomonas aeruginosa BiofilmsSemantic proximity Read ↗

Novel Therapeutic Strategies Applied to Pseudomonas aeruginosa Infections in Cystic FibrosisSemantic proximity Read ↗

Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Infection in an Ex Vivo Pig Model of the Cystic Fibrosis LungSemantic proximity Read ↗

Bacterial extracellular vesicle: A non-negligible component in biofilm life cycle and challenges in biofilm treatmentsSemantic proximity Read ↗

Current concepts on Pseudomonas aeruginosa interaction with human airway epitheliumSemantic proximity Read ↗

Placentrex disrupts the biofilm formation of <i>Pseudomonas aeruginosa</i> through multi-target transcriptional reprogrammingSemantic proximity Read ↗

Approaches to Targeting Bacterial Biofilms in Cystic Fibrosis AirwaysSemantic proximity Read ↗

Pharmacological strategies for targeting biofilms in otorhinolaryngologic infections and overcoming antimicrobial resistance (Review)Semantic proximity Read ↗

MicroRNA-762 Is Upregulated in Human Corneal Epithelial Cells in Response to Tear Fluid and Pseudomonas aeruginosa Antigens and Negatively Regulates the Expression of Host Defense Genes Encoding RNase7 and ST2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.