Article

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

2021-03-30

Abstract excerpt

The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire or generate lists of differentially expressed genes between control and SARS-CoV-2-infected samples. Using a rank-based patte...

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Literature Corpus work: e9e2f9d3-0a63-5179-bd02-203db5331993
DOI: 10.21203/rs.3.rs-333578/v1

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