Article

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

2020-10-23

Abstract excerpt

The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire or generate lists of differentially expressed genes between control and SARS-CoV-2-infected samples. Using a rank-based patte...

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Literature Corpus work: 2d6e6114-7df8-5b3d-9407-6a74986faadc
DOI: 10.1101/2020.10.23.352666

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