Article

LC3 and NLRC5 Interaction Inhibits NLRC5-Mediated MHC Class I Antigen Presentation Pathway in Endometrial Cancer

2021-11-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The major histocompatibility complex class I (MHC- I) transactivator, nucleotide binding oligomerization domain-like receptor family caspase recruitment domain containing 5 (NLRC5), serves as a target for immune evasion in many cancers, including endometrial cancer (EC). An inhibition of autophagy can contribute to immunotherapy by assisting the MHC-I-mediated a...

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Literature Corpus work: e94d7c67-bfb0-5d0e-8b58-0f53f5ec6a2d
DOI: 10.21203/rs.3.rs-1018081/v1

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