Article

Endosomal LRBA regulates the endo-lysosomal pathway

2024-02-08

Abstract excerpt

Deleterious mutations in the LRBA (Lipopolysaccharide Responsive Beige-like Anchor protein) gene cause severe childhood immune dysregulation. The clinical manifestations of LRBA deficiency syndrome are highly variable. Thus, the complexity of the symptoms involving multiple organs and the broad range of unpredictable clinical manifestations complicate the choice of therapeutic interventions. Although LRBA has bee...

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Literature Corpus work: e9137e35-49a8-5e14-b7c6-e8a37988df96
DOI: 10.1101/2024.02.07.579084

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