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Disparities in ABO Blood Type Determination Across Diverse Ancestries: A Systematic Review and Validation in the<i>All of Us</i>Research Program

2024-02-24

Abstract excerpt

<h4>Background</h4> ABO blood types have widespread clinical use and robust associations with cardiovascular disease. Many studies determine ABO blood types using tag single nucleotide polymorphisms (tSNPs) to characterize functional variation. However, tSNPs with low linkage disequilibrium (LD) may promote misinference of ABO blood types, particularly in diverse populations. <h4>Methods</h4> Bibliographic databas...

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Literature Corpus work
e902ab18-fd75-5aea-91c8-469a51b2765a
DOI
10.1101/2024.02.21.24302372
Open publication

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Disparities in ABO Blood Type Determination Across Diverse Ancestries: A Systematic Review and Validation in the<i>All of Us</i>Research ProgramDOI 10.1101/2024.02.21.24302372
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