Article

Implications of covariate induced test dependence on the diagnostic accuracy of latent class analysis in pulmonary tuberculosis

2021-09-15

Abstract excerpt

<h4>Background: </h4> Lack of a perfect reference standard for pulmonary tuberculosis (PTB) diagnosis complicates assessment of accuracy of new diagnostic tests. Alternative strategies such as discrepant resolution and use of composite reference standards may lead to incorrect inferences on disease prevalence and diagnostic test sensitivity and specificity. Latent class analysis (LCA), a statistical method for ana...

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Literature Corpus work: e8b0d3e3-fdbe-563f-a547-9e94513585e0
DOI: 10.21203/rs.3.rs-900353/v1

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