Article
Clinical proof of concept for anti-FGF2 therapy in exudative age-related macular degeneration: phase 1 and phase 2 trials in treatment-naïve and anti-VEGF pretreated patients
2023-03-08
Abstract excerpt
<title>Abstract</title> <p>Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents are the first-line treatment for exudative/wet age-related macular degeneration (wet AMD). Alternative mechanisms of action may be helpful for treatment of this very common disease. Here we investigated an anti-fibroblast growth factor-2 (FGF2) aptamer, RBM-007, a next generation therapeutic for the treatme...
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Identifiers and source
- Literature Corpus work
- e80a1170-b0d1-5985-a715-e4d838cafd95
- DOI
- 10.21203/rs.3.rs-2656731/v1
