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Preclinical development of a dual targeting bicistronic gene therapy approach for the treatment of wet age-related macular degeneration

2024-07-22

Abstract excerpt

<title>Abstract</title> <p>Age-related macular degeneration (AMD) continues to be a leading cause of severe vision impairment affecting millions worldwide. The late stages of AMD are characterized by outer retinal atrophy (geographic atrophy, GA), or neovascularization associated with subretinal and/or intraretinal exudation (exudative neovascular or ‘wet’ AMD). Intravitreal (IVT) administration of anti-vascular...

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Literature Corpus work
a5780130-9ad9-53e3-b8b4-ada090055b19
DOI
10.21203/rs.3.rs-4636180/v1
Open publication

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Preclinical development of a dual targeting bicistronic gene therapy approach for the treatment of wet age-related macular degenerationDOI 10.21203/rs.3.rs-4636180/v1
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