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A Practical Framework for Constructing Population-Specific and Alternate-Contig-Aware Genome References: A case study of Vietnam

2026-08-27

Abstract excerpt

Current studies in human genomics typically rely on the standard genome reference GRCh38 which is known to be biased toward populations of European ancestry and therefore has limitations when applied to other populations. Although various graph-based pangenome references were constructed for several populations to deal with this bias, their usage in practice is currently still limited compared to linear genome ref...

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Literature Corpus work
e7e198f8-a3b5-5769-9e36-f5827396cb0c
DOI
10.64898/2026.08.24.746817
Open publication

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A Practical Framework for Constructing Population-Specific and Alternate-Contig-Aware Genome References: A case study of VietnamDOI 10.64898/2026.08.24.746817
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