Comparisons of Differential Analysis Methods between mRNAs and Parkinson’s Disease

Abstract excerpt

<title>Abstract</title> <p>Background Parkinson's disease (PD) is a chronic, progressive neurodegenerative illness presenting motor and nonmotor symptoms. The primary pathology involves the gradual degeneration of dopaminergic neurons substantia nigra in the midbrain, causing motor dysfunction. PD is linked with changing gene expression, especially in the dopamine-dependent oxidative stress passages. Messenger R...

Topics

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• Genetic Neurodegenerative Diseases
• Neuroinflammation and Neurodegeneration Mechanisms
• Neurological diseases and metabolism
• Neurological disorders and treatments
• Nuclear Receptors and Signaling
• Parkinson's Disease Mechanisms and Treatments
• RNA regulation and disease

Identifiers and source

Literature Corpus work

e7d13ef7-222d-5ec8-9273-d2e8906d15e7

DOI

10.21203/rs.3.rs-4380255/v1