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Article

Treating the Network: Targeted inhibition of two specific microRNAs in the brainstem prevents the development of hypertension

2020-03-12

Abstract excerpt

We here test the concept that disease states may result not from a single cause but from small changes in a network that are collectively significant. We recently showed that development of hypertension (HTN) in the spontaneously hypertensive rat (SHR) model of human essential hypertension is accompanied by changes in microRNA expression levels in the brainstem tracking the development of HTN 1,2 . This led to th...

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Identifiers and source

Literature Corpus work
e7b95c99-f35f-561f-b092-af2c3b7b7b9f
DOI
10.1101/2020.03.11.987966
Open publication

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