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Integrated Machine Learning-PanGWAS Reveals Chromosome-Encoded Persistence Networks and Plasmid Plasticity in Recurrent Urinary Tract Infection in <i>Escherichia coli</i>

2026-05-22

Abstract excerpt

<h4>Background</h4> Recurrent urinary tract infections(rUTI) represent a major clinical challenge due to persistent clinical symptoms, repeated antibiotic exposure, and increased risk of multidrug resistance. Further clinical management of rUTI remains challenging, as existing diagnostic and treatment guidelines are largely designed for uncomplicated, acute infections. Though uropathogenic Escherichia coli (UPEC...

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Literature Corpus work
e761b345-fd6d-5c29-8852-452a8feb074c
DOI
10.64898/2026.05.20.26353739
Open publication

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Integrated Machine Learning-PanGWAS Reveals Chromosome-Encoded Persistence Networks and Plasmid Plasticity in Recurrent Urinary Tract Infection in <i>Escherichia coli</i>DOI 10.64898/2026.05.20.26353739
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