Article
Temperature-dependent IL6-STAT3-HSP90 axis mediates aquatic viral entry
2022-04-27
Abstract excerpt
<title>Abstract</title> <p>IL6-STAT3 signaling is a canonical pro-inflammatory pathway that is evolutionarily conserved and plays important roles in both temperature related responses and virus infection. However, our understanding of the molecular mechanisms underpinning the temperature-dependent pathogenesis of aquatic viral diseases remains rudimentary. Here we deploy Grass carp reovirus (GCRV) infection as a...
Topics
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- Animal Disease Management and Epidemiology
- Aquaculture disease management and microbiota
- Heat shock proteins research
- interferon and immune responses
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Viral Infections and Vectors
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- e7042f15-5342-59dd-b24a-618e856e33b2
- DOI
- 10.21203/rs.3.rs-1564595/v1
