Back to search

Article

Loss of imprinting control of the lncRNA H19-fetal mitogen IGF2 gene cluster in the decidual microenvironment of patients with idiopathic spontaneous miscarriages

2021-11-10

Abstract excerpt

<title>Abstract</title> <p>Miscarriage, the spontaneous loss of a pregnancy before the fetus achieves viability, is a common complication of pregnancy. Decidualization plays a critical role in the implantation of the embryo. To search for molecular factors underlying miscarriage, we explored the role of long noncoding RNAs (lncRNAs) in the decidual microenvironment, where the molecular crosstalk at the feto–mater...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e6df8df5-da8c-52e4-a97f-decc7fe675f0
DOI
10.21203/rs.3.rs-1044267/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Loss of imprinting control of the lncRNA H19-fetal mitogen IGF2 gene cluster in the decidual microenvironment of patients with idiopathic spontaneous miscarriagesDOI 10.21203/rs.3.rs-1044267/v1
Placenta-specific epimutation at H19-DMR among common pregnancy complications: its frequency and effect on the expression patterns of H19 and IGF2Semantic proximity
Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity
Aberrant DNA Methylation of IGF2-H19 Locus in Human Fetus and in Spermatozoa From Assisted Reproductive TechnologiesSemantic proximity
Quantitative allele-specific expression and DNA methylation analysis of H19, IGF2 and IGF2R in the human placenta across gestation reveals H19 imprinting plasticity.Semantic proximity
Gene expression pattern of <i>IGF2</i> , <i>PHLDA2</i> , <i>PEG10</i> and <i>CDKN1C</i> imprinted genes in spontaneous miscarriages or fetal deathsSemantic proximity
DNA methylation profiling of placental villi from karyotypically normal miscarriage and recurrent miscarriage.Semantic proximity
DNA methylation at H19/IGF2 ICR1 in the placenta of pregnancies conceived by in vitro fertilization and intracytoplasmic sperm injectionSemantic proximity
Alterations in expression of imprinted genes from the H19/IGF2 loci in a multigenerational model of intrauterine growth restriction (IUGR)Semantic proximity
Expression of the imprinted IGF2 and H19 genes in the endometrium of cases with unexplained infertility.Semantic proximity
RNA sequencing of chorionic villi from recurrent pregnancy loss patients reveals impaired function of basic nuclear and cellular machinerySemantic proximity
Epigenetic regulation of the <i>Igf2/H19</i> gene clusterSemantic proximity
Altered gene expression of VEGF, IGFs and H19 lncRNA and epigenetic profile of H19-DMR region in endometrial tissues of women with endometriosisSemantic proximity
Select a neighboring publication to make it the new centre.