Gene expression pattern of <i>IGF2</i> , <i>PHLDA2</i> , <i>PEG10</i> and <i>CDKN1C</i> imprinted genes in spontaneous miscarriages or fetal deaths

Abstract excerpt

Genomic imprinting is defined as an epigenetic modification that leads to parent-of-origin specific monoallelic expression. Some current research on the fetal control growth has been focused on the study of genes that display imprinted expression in utero. Four imprinted genes, two paternally expressed (IGF2 and PEG10) and two maternally expressed (PHLDA2 and CDKN1C), are well known to play a role in fetal growth...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epigenetics and DNA Methylation
• Share to Genetic Syndromes and Imprinting
• Share to Prenatal Screening and Diagnostics