Article

Reduced <i>LANCL1-AS1</i> in old human skeletal muscle diminishes mitochondrial activity, shortens mt-mRNA poly(A) tails, and suppresses myogenesis

2026-07-06

Abstract excerpt

<h4>SUMMARY</h4> Regeneration of skeletal muscle preserves muscle mass and function, which decline with age. Here, we sought to identify long noncoding (lnc)RNAs involved in skeletal muscle myogenesis and potentially relevant to muscle aging. Cross-sectional analysis of skeletal muscle transcriptomes from healthy 22-through 89-year-old individuals revealed lncRNA LANCL1-AS1 among the top declining transcripts. C...

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Literature Corpus work: e66ae895-579d-5585-b852-c3d5e6203d5a
DOI: 10.64898/2026.07.05.736613

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