Article

A randomized double-blind placebo-controlled clinical trial of Guanfacine Extended Release for aggression and self-injurious behavior associated with Prader-Willi Syndrome

2024-08-22

Abstract excerpt

<h4>Introduction: </h4> Prader-Willi Syndrome (PWS), a rare genetic disorder, affects development and behavior, frequently resulting in self-injury, aggression, hyperphagia, oppositional behavior, impulsivity and over-activity causing significant morbidity. Currently, limited therapeutic options are available to manage these neuropsychiatric manifestations. The aim of this clinical trial was to assess the efficacy...

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Literature Corpus work: e51f5202-7fef-56a0-bed3-45ab405bc911
DOI: 10.1101/2024.08.22.24312419

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