Article

Diazoxide choline (Vykat XR) for treatment of hyperphagia and obesity in Prader-Willi syndrome: A therapeutics bulletin of the American College of Medical Genetics and Genomics (ACMG)

2026-08-01

Abstract excerpt

Prader-Willi syndrome (PWS) is a rare genetic disorder with an estimated incidence of 1 in 21,000 caused by the loss of function of specific genes on the paternal chromosome 15 (15q11-q13 region). It affects multiple systems and is characterized by distinctive dysmorphic features along with a set of clinical features that evolve over time. The phenotype was first described in 1956,1 and over time, the clinical spe...

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Literature Corpus work: 4e09d7b8-4d6e-5f7b-b529-c8ab12296dd2
DOI: 10.1016/j.gimo.2026.104412

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