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Linking White-Matter Development to Clinical Variation in Autism: Longitudinal Normative Modelling of Fractional Anisotropy (FA) in the EU-AIMS LEAP Cohort

2025-11-26

Abstract excerpt

<h4>Background</h4> Autism is characterised by neurobiological and clinical heterogeneity, which often limits the sensitivity of traditional group comparisons. Longitudinal normative modelling offers a way to capture heterogeneity and to describe an individual’s brain–behaviour relationships beyond diagnostic categories. <h4>Methods</h4> We analysed diffusion MRI scans from 3 waves of the EU-AIMS Longitudinal Eu...

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Literature Corpus work
e4dfaa84-5376-5403-a92f-f5cffca04f53
DOI
10.1101/2025.11.25.690402
Open publication

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Linking White-Matter Development to Clinical Variation in Autism: Longitudinal Normative Modelling of Fractional Anisotropy (FA) in the EU-AIMS LEAP CohortDOI 10.1101/2025.11.25.690402
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