Article
Endogenous AhR agonist FICZ accumulates in rainbow trout (Oncorhynchus mykiss) alevins exposed to a mixture of two PAHs, retene and fluoranthene.
2022-05-03
Abstract excerpt
Multiple studies have reported synergized toxicity of PAH mixtures in developing fish larvae relative to the additive effect of the components. From a toxicological perspective, multiple mechanisms causing synergism has been proposed, such as increased accumulation of PAH, saturated xenobiotic metabolism capacity, and increased oxidative stress. Another potential contributor to synergism is the accumulation of end...
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Identifiers and source
- Literature Corpus work
- e352f5bc-d338-55a2-87d3-2ee9a9d216cd
- DOI
- 10.21203/rs.3.rs-1592800/v1
