Back to search

Article

Gene expression levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence and risk of death in cervical cancer

2022-08-03

Abstract excerpt

<h4>Background</h4> Up to 74% of patients with cervical cancer (CC) may experience recurrence after their treatment, and most of them are identified late when only the clinical parameters are used, which decreases their chances of recovery. Molecular markers can improve the prediction of clinical outcome and identify therapeutic targets in CC. Glycolysis is altered in 70% of CCs, so it could be a metabolic pathway...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e2fb4288-0df7-506a-bbaf-58a75c5e2c80
DOI
10.1101/2022.08.02.22277946
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Gene expression levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence and risk of death in cervical cancerDOI 10.1101/2022.08.02.22277946
Identification and validation of a six-gene signature associated with glycolysis to predict the prognosis of patients with cervical cancerSemantic proximity
Comprehensive Analysis of the Glycolysis-Related Gene Prognostic Signature and Immune Infiltration in Endometrial CancerSemantic proximity
Single-cell transcriptome analysis revealed heterogeneity in glycolysis and identified IGF2 as a therapeutic target for ovarian cancer subtypesSemantic proximity
Identification of Lactate-Related Subgroups and Prognostic Model in Triple-Negative Breast CancerSemantic proximity
Comprehensive Analysis of the Association Between the Glycolysis Prognostic Risk Signature and Immune Infiltration in Endometrial CancerSemantic proximity
Comprehensive Analysis of Lymph Nodes Metastasis Associated Genes in Cervical Cancer and its Significance in Treatment and PrognosisSemantic proximity
Glycolysis rate-limiting enzyme PFKP: A pan-cancer predictor for prognostic significant, immunological correlation, and drug sensitivity predictionSemantic proximity
Lactate metabolism-related genes to predict the clinical outcome and molecular characteristics of endometrial cancerSemantic proximity
A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancerSemantic proximity
A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancerSemantic proximity
Glycolysis-related gene expression profiling serves as a novel prognosis risk predictor for human hepatocellular carcinomaSemantic proximity
Combining glycolysis and oxidative stress characterizations to assess prognosis in ovarian cancerSemantic proximity
Select a neighboring publication to make it the new centre.