Article

Potassium channel-driven bioelectric signaling regulates metastasis in triple-negative breast cancer

2021-04-06

Abstract excerpt

There is a critical need to better understand the mechanisms that drive local cell invasion and metastasis to develop new therapeutics targeting metastatic disease. Bioelectricity is an important mediator of cellular processes and changes in the resting membrane potential (RMP) are associated with increased cancer cell invasion. However, the mechanism is not well understood. Our data demonstrate that altering the...

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Literature Corpus work: e2a7bd46-6ab4-5f00-a985-0a2d5533096e
DOI: 10.1101/2021.04.06.438714

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