Article

Benefit-Risk Assessment of Medical Products Using Bayesian Multi-Criteria Augmented Decision Analysis for Clinical Development

2023-09-02

Abstract excerpt

Multi-criteria decision analysis (MCDA) is a benefit-risk assessment tool that evaluates multiple competing benefit and risk endpoints simultaneously. MCDA has the potential to aid sponsors in making effective and informed go/no-go decisions for clinical development programs. MCDA involves assigning weights to benefit and risk endpoints based on their relative importance (i.e., utility weight) and using them to co...

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Literature Corpus work: e238fb02-cbba-5f1e-aea2-0af645c4b120
DOI: 10.1101/2023.08.31.23294918

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