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Article

Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the Foot-and-Mouth Disease Virus capsid

2018-02-24

Abstract excerpt

Although recombination is known to occur in FMDV, it is considered only a minor determinant of virus sequence diversity. This is because recombination appears to be highly suppressed at phylogenetic scales; inter-serotypic recombination events are rare; and in those a mosaic structure is present whereby recombination only occurs almost exclusively in non-structural proteins. Here we show that co-inoculation of clo...

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Literature Corpus work
e21bd470-47fd-5ad8-a415-5227fd4751cd
DOI
10.1101/271239
Open publication

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Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the Foot-and-Mouth Disease Virus capsidDOI 10.1101/271239
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